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In 1866, Russian scientist Alexander Saytzeff isolated a most curious and peculiar chemical chemical compound. It was crystalline, odor-less, not-toxic and had a garlic-similar taste when consumed. At the time, Saytzeff had no way to predict that his discovery was going to prove highly controversial throughout its unabridged medical history, that it was going to exist tested in thousands of studies and provide miraculous relief for numerous patients.

I'grand talking here nigh dimethyl sulfoxide (DMSO), an organic sulfur compound which was used but as an industrial solvent, that is, until its medical properties were discovered in 1963 by a research squad headed by Stanley W. Jacob, MD.

DMSO is a past-production of kraft pulping (the 'sulfate procedure') which converts woods into wood pulp leaving almost pure cellulose fibers. Equally industrial as it may sound, the process simply entails a treatment of wood chips with a mixture of sodium hydroxide and sodium sulfide, known as white liquor, breaking the bonds which link lignin (from the Latin word lignum, pregnant wood) to the cellulose.

DMSO is useful as a hurting reliever and likewise in burns, acne, arthritis, mental retardation, strokes, amyloidosis, caput injury, scleroderma, information technology soothes toothaches, eases headaches, hemorroids, muscle strains, it prevents paralysis from spinal-chord injuries and softens scar tissues. In fact, it is useful in well over 300 ailments and is safe to use. Yous might think that a compound that has and then many alleged uses and benefits should be automatically suspect, so let'due south accept a shut look at its properties and the data available and we'll shed some light in this miraculous chemical.

Sulfur: The Stuff of Life

DMSO is an intermediate product of the global Sulfur Cycle which distributes bioavailable sulfur for all beast and constitute life (Parcell, 2002). Sulfur compounds are establish in all trunk cells and are indispensable for life, they are needed for a number of chemical reactions involved in the detoxification of drugs and other harmful toxins, and they have potential clinical applications in the treatment of a number of conditions such every bit low, fibromyalgia, arthritis, interstitial cystitis, athletic injuries, congestive heart failure, diabetes, cancer, and AIDS (Parcell, 2002). Among the sulfur compounds, DMSO is probably the one that has the widest range and greatest number of therapeutic applications e'er shown for whatsoever other unmarried chemical. It has around 40 pharmacological properties that may be beneficial in the prevention, relief or reversal of numerous diseases (Morton, 1993).

Someone complained to Dr. Jacob of a splitting headache and gave him permission to utilise some DMSO afterward hearing of its capabilities. The headache was gone in minutes, came back in four hours, and left for good after DMSO was applied a second time. Used for one purpose, sometimes it did another; put on a cold sore, inside a few hours it cleared upwards a adult female's sinusitis. A adult female who had had a stroke found subsequently DMSO was painted on her painful jaw that she could at present write with her paralyzed manus and could walk ameliorate. (Haley, 2000)

Therapeutic Backdrop

DMSO is an effective pain killer, blocking nerve conduction fibers that produce pain. It reduces inflammation and swelling by reducing inflammatory chemicals. Information technology improves blood supply to an area of injury by dilating blood vessels and increasing delivery of oxygen and by reducing claret platelet stickiness. It stimulates healing, which is a key to its usefulness in any status. It is among the most strong free radical scavengers known to man, if non the virtually potent one. This is a crucial mechanism since some molecules in our bodies produce an unequal number of electrons and the instability of the number causes them to destroy other cells. DMSO hooks on to those molecules and they are then expelled from the body with the DMSO.

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Dr Stanley Jacob working with DMSO in the 1960s

DMSO too penetrates the pare and the blood-encephalon barrier with ease, penetrating tissues, and entering the bloodstream. Furthermore, DMSO protects the cells from mechanical impairment and less of it is needed to reach results as time passes every bit oppossed to near pharmaceuticals where increasing doses are required. It has a calming effect in the central nervous arrangement and it reaches all areas of the torso, when absorbed through the skin, including the brain. That is, DMSO applied to 1 area ofttimes leads to hurting relief in some other location due to its systemic effect.

It acts as a carrier for other substances or drugs and it also potentiates their consequence. In fact, sure drugs dissolved in DMSO, such as corticoids, antibiotics and insulin, may exist used in a lower dose than usual without reducing their therapeutic efficacy and in addition, their undesirable side effects are greatly diminished. Also, drugs are able to pass through the blood-brain bulwark which is usually impenetrable.

DMSO promotes the excretion of urine and functions as a muscle relaxant. Information technology boosts the immune system, increasing the production of white cells and macrophages that destroy strange cloth and pathogens in the body. It as well has anti-bacterial, anti-viral and anti-fungal properties. DMSO besides increases the permeability of jail cell membranes, allowing a flushing of toxins from the cell.

DMSO has radioprotective properties against lethal and mutagenic effects of Ten-rays in cells, cellular systems and whole animals. Information technology as well has cryoprotective properties, meaning that it is capable of protecting confronting injury due to freezing.
DMSO has also been shown to take cholinesterase properties (Sams, 1967), in other words, information technology inhibits an enzyme from breaking down acetylcholine, increasing both the level and duration of action of this of import neurotransmitter. Acetylcholine is responsible for learning and retentiveness and is also calming and relaxing. Acetylcholine is too a major gene in regulating the immune organization, interim as a major brake on inflammation in the torso.

As a source of sulfur, DMSO aids in heavy metal detoxification. Sulfur binds with toxic heavy metals (mercury, lead, aluminum, cadmium, arsenic, nickel) and eliminates them via urination, defecation and sweating.

FDA and Big Pharma Obstacles

DMSO is sold in health food stores, mail-order outlets, on the Internet, and in well-nigh countries effectually the world. It is used by millions for its health benefits yet in the U.S., DMSO has FDA approval only equally a preservative of stalk cells, os marrow cells, and organs for transplant, and for interstitial cystitis - a painful inflammatory condition of the bladder which is very hard to treat with other therapies.

That DMSO has not found favor as a remedy for other medical conditions is partly due to the disability to examination it in double-blind experiments. Blind studies, as the name suggests, requires that a report be done without knowing which patient is taking the placebo or the drug. In the case of the DMSO, a blind report is impossible since the peculiar garlic-similar taste and smell (no matter the route of awarding) gives it away and no satisfactory placebo could exist devised that would mimic this particular consequence of DMSO (Steinberg, 1967).

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The FDA and 'big pharma' would prefer nosotros remain dependent on their drugs

If yous search for DMSO on the U.S. National Library of Medicine (pubmed.gov), you'll get most 30,000 indexed results, making it one of the most studied compounds of our time. Nevertheless, we are led to believe that DMSO can't laissez passer the required regulations for its approval in other medical conditions even though its effectiveness and depression toxicity contour is unquestionable.

You lot see, DMSO is a mutual chemical that tin can be manufactured cheaply. No drug company can get an exclusive patent since it is also a natural chemical compound, therefore at that place is no significant financial render. In fact, an executive of a major drug company is quoted as maxim, "I don't care if DMSO is the major drug of our century and we all know it is, information technology isn't worth it to usa" [CBS Television show lx minutes with Mike Wallace, The Riddle of DMSO]. If DMSO were to be approved by the FDA, information technology would be competetive and drug companies would be unable to hold the patents. In the words of the director of the Bureau of Drugs of the FDA, J. Richard Crout, Chiliad.D., "DMSO is a low toxicity and safe compound (...) I think that it is a fact of life that drug companies are not going to invest in something unless they think there is some financial render" [CBS Boob tube testify 60 minutes with Mike Wallace, The Riddle of DMSO].

Despite restrictions on the use of DMSO, thousands of Americans buy it on the 'black market place' each yr, its popularity due not to publicity, merely rather 'word of mouth'. When you have something that relieves all kinds of ailments, including some life-threatening ones, people naturally recommend it to friends and family!

In Perspective

In the 1960s, research with DMSO on humans was temporarily halted after certain animals treated with DMSO were plant to take changes in the eye lens. Some of these changes resembled those seen in aging dogs (Gordon, 1967), but all the same, inquiry was gradually restarted after no testify was found of center changes in humans. Equally Daniel Haley reports in his book Politics in Healing: "Tests in rabbits, dogs, and pigs (merely not humans) had shown some problems. When quantities of DMSO equal to near ten times the maximum human dose were given every day over a period of vi months, slight changes in the lenses of the animals' eyes would issue, plenty to produce a slight nearsightedness. The lens changes were not enough to cause dogs difficulty when running - they didn't bump into things - and in some cases, the changes disappeared after the massive DMSO doses were stopped. In no test at that fourth dimension or since has DMSO ever caused cataracts, either in animals or in humans" (Haley, 2000).

In fact, DMSO is effective for macular degeneration and retinal illness, both diseases of the centre. This effectiveness was get-go discovered when patients with retinitis pigmentosa, a retinal disease, were taking DMSO for certain musculoskeleteal disorders. They sensed that their vision had improved and some had remarkable results (Morton, 1993).

As far every bit eyes are concerned, the evidence on DMSO is quite to the reverse. When several patients treated with DMSO for muscular bug reported to Dr. Jacob that their vision had improved, he sent them to Dr. Robert O. Colina, ophthalmologist at the Academy of Oregon Medical School. Confirming the favorable changes, Dr. Loma began his own experiments with DMSO (afterwards it was known that the lens changes did not happen in humans). His research showed drops of 50% DMSO to be effective in retinitis pigmentosa and macular degeneration, and presented a report on this at the New York Academy of Sciences symposium in 1971. (Haley, 2000)

In contrast, the number of medication-related deaths in the U.South. is estimated at over 200,000 a twelvemonth, making medications the third or 4th leading cause of death (Pezzalla, 2005). Even mutual pain relievers called NSAIDs, examples of which include Advil, Motrin, Aleve and aspirin, business relationship for an estimated 7,600 deaths and 76,000 hospitalizations in the U.S. every year (Tamblyn et al, 1997). Taking this into consideration, information technology is safety to declare that DMSO is amidst the safest substances in the earth today. In fact, the classic examination for toxicity -the LD-l test - measures the lethal dose (LD) at which half of a group of test animals is killed. The LD-l tests for aspirin and DMSO show that aspirin is vii times more toxic than DMSO (Haley, 2000).

Quick Guide and Ailments

DMSO is generally practical to the peel in a gel, cream, or liquid. Information technology can be taken by oral cavity or equally an intravenous injection, in many cases along with other drugs. It has also been administered subcutaneously, intramuscularly, intraperitoneally, intrathecally, by inhalation, instilled into the centre, on the mucous membranes, and into the urinary bladder. Strenghs and dosages vary widely.

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If you are simply dealing with pain or an injury, utilise a topical application. Don't drink information technology. Drinking it is for serious detoxing and other internal necessities. If you use a rose scented DMSO foam, chances are that nobody volition exist able to smell DMSO's garlic-like smell.

The usual oral dose of DMSO is one teaspoon per solar day of DMSO 70% (Morton, 1993). But since it tin trigger detoxification reactions and DMSO'south full excretion from the body tin take several days, it is best to do information technology only once a week. Start with half a teaspoon of DMSO 50% and increase to a teaspoon of DMSO 70% only if whatsoever possible detoxification reaction is well tolerated.

When y'all use liquid DMSO in the skin, let information technology dry for over 20 to thirty minutes before wiping the rest out. The skin must be clean, dry, and unbroken for any topical use of DMSO. The face up and the cervix are more sensitive to DMSO and no college concenrations than l% should be applied there. Topical concentrations of DMSO should be kept below 70% in areas where in that location is a reduction of circulation. When threescore to 90% DMSO is applied to the skin, warmth, redness, itching, and somtimes local hives may occur. This usually disappears within a couple of hours and using natural aloe vera, gel or cream, volition help counteract or forestall this effect. When 60 to 90% DMSO is applied to the palm on the mitt, the skin may wrinkle and stay that way for several days.

"My brother put some DMSO gel (seventy% dmso, xxx% aloe vera) on his shoulders and lower part of neck because he had muscle hurting/soreness in that area, and it caused skin redness/irritation for a few hours, although it did diminish the muscle soreness besides...my grandma has rheumatoid arthritis that made her legs slap-up upwards and hurt continuously, and I had her apply the aforementioned DMSO gel, and afterwards about two-3 days of applying it once a day, the swelling was xc% gone, and I think within 4-5 days it was 100% gone, and she said the pain diminished as well." - Michael Shatskiy, Los Angeles, California, United States

Chronic hurting patients often take to apply the substance for 6 weeks before a change occurs, but many report relief to a caste that had not been able to obtain from whatever other source. In general, the greater the chronicity of the disorder, the longer the treatment with DMSO must be employed in order to accomplish palliation (Steinberg , 1967).

Mutual health problems for which people volition apply topical DMSO at abode include acute musculoskeletal injuries and inflammations. The earlier DMSO is used, the more dramatic the consequence. A seventy% concentration of DMSO mixed with water in volumes ranging from 8 to 12 ml, practical on and around the injury in a broad area at least three times daily, will accept a healing bear on in iv out ot 5 people.

Arthritis, Sprains, Strains

Information technology provides rapid amelioriation of pain and increased mobility and reduction of inflammation when used topically. You lot tin can see a positive response within 5 to 20 minutes and usually lasting for 4 to 6 hours. (Steinberg, 1967).

"Applying DMSO where it hurt to a half-dozen-year-quondam wasted from rheumatoid arthritis, in a half hour the child could movement her shoulder and turn her head for the get-go time in 2 years. Persuaded to try walking, she managed a few steps and so outburst into tears. "Why are you crying?" Dr Jacob asked her. "Because it doesn't hurt anymore", she replied. (Haley, 2000)
"My brother has arthritis of the spine. He is in pain and bedridden more than than half the time. When he is treated with DMSO, he is able to atomic number 82 a normal, active life... Just one application of this inexpensive, rubber DMSO inverse my brother from a grimacing patient into an active, pain-free man in exactly 30 minutes!" (Haley, 2000)
June Jones, one time quarterback and afterward jitney of the Atlanta Falcons pro-football squad, had a bursitis calcification in his right shoulder. His career almost didn't happen as he could inappreciably elevator his arm, permit lone throw a football. But he was aware of DMSO and had used DMSO for sprains, like thousands of others. He received a shot of DMSO in the shoulder and afterwards using DMSO for thirty days straight, the calcification disappeared. (Haley, 2000)

Stroke

Given soon after a stroke, DMSO can dissolve the clot that causes the stroke, restoring circulation and fugitive paralysis. Once DMSO gets into the body either daubed on the peel, given in I.V., or past rima oris, it permeates the body and crosses the brain barrier, then fifty-fifty taken orally information technology tin ameliorate circulation. Ideally it should be I.5.

Fifty-fifty though DMSO twoscore% causes a prolongation of haemorrhage time, it is still indicated for use in treating embolic or hemorrhagic stroke. DMSO is superior to any other treatment for wounds to the brain where a great deal of bleeding is present (Morton, 1993).

1 man who had a stroke at 7:30 AM refused to go to the hospital until after his wife had spoken with Dr. Stanley Jacob, which didn't happen until half-dozen:30 PM. Starting at 7 PM the twenty-four hours of the stroke, she gave him one ounce of 50% DMSO in a little orange juice every 15 minutes for two hours so every half hour for two hours. The next day, her husband was better and before long returned to normal. A substance that tin stop a stroke as it'south happening is something many might want in their home medicine chest .(Haley, 2000)

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Angina, Center Attacks, Injuries of the Encephalon and Spinal Chord

DMSO may help neutralize harmful furnishings on the middle and brain in medical disorders involving the head and spinal chord injury, stroke, memory dysfunction, and ischemic heart disease (Jacob, de la Torre, 2009). A 40% DMSO solution should be administered inside iv hours to be effective, within 90 minutes is all-time.

After I.5. administration of DMSO, there is an elevation in the amount of spinal cord blood flow to the region of trauma. Ane of the start things that happens after spinal string trauma is that a reduction of oxygen and blood menstruation sets in, inasmuch as the blood vessels constrict or shut down... Without some treatment, the tissue swells. Eventually, this leads to paralysis. In a cerebral stroke, the animate being will either become comatose or lethargic or die. With DMSO infusion immediately after injury (or stroke) all this is prevented. - Dr. Jack de Ia Torre, professor of physiology and neurosurgery at the University of New Mexico
Dr. Stanley Jacob has even given DMSO intravenously to people who were already paralyzed - paraplegics - and some regained use of limbs. One homo, quadraplegic, recovered enough to go through college and so to piece of work in a banking company. (Haley, 2000)

Infections

When combined with antibiotics, DMSO volition convert bacteria which are resistant to a given antibiotic to existence sensitive to that same antibiotic and probably a eighty to 90 per cent solution of DMSO will be required in order to be clinically useful ( Pottz, Rampey, Benjamin,1967). DMSO has been used to transport antibiotics to hard-to-reach areas of the trunk with excellent results, such as the bone marrow and brain (Sanders, 1967).

DMSO tin can dissolve a virus protein coating, leaving the virus core unprotected with its nucleic acid exposed to the immune arrangement. Practical topically, information technology alleviates the lesions that occur as a result of Canker Zoster, shingles (Morton, 1993).
Placed into the nostrils or topically in the face, DMSO tin open up blocked sinuses inside a few minutes and it has been used with sucess in patients with polyps (Marvin, 1967).

DMSO can clear upwardly mucilage illness and reduce molar decay and their pain by painting it on the involved areas.

"I have some pharmaceutical grade DMSO and I pour about two teaspoons in a glass in the evening, put my 20 mg of doxycycline in it, add well-nigh 2 teaspoons of distilled water, and then classy information technology around in my mouth for about 2 or 3 minutes and then eat it. So I guess it is well-nigh 50% solution. It's really working on my mouth. That inflamed surface area of my jaw has calmed down about 70% in but a couple of days. Or more, actually. I wait information technology to be completely soothed by tomorrow subsequently tonight's dose of DMSO." - L., Toulouse, France

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Several books have been published on the benefits of DMSO

Keloids, Scars, Burns, Bruises

A concentration of fifty to 80% put on two or 3 times a day will flatten a raised scar after several months. It is of considerable value in superficial burns (Goldman, 1967) and when applied speedily to an injury, it can eliminate whatever bruising.

"I have been applying it to my face for 2 weeks... I had a bout of acne in March, and this healed the damage pretty well but what amazed me is that my hyperpigmentation (melasma) has also faded very noticeably. In fact, it's amazing!" - HG, United States
"I diluted a l% solution and applied information technology topically to the inflamed lymph node. I practical it again this evening. I am totally amazed! In that location is a noticeable decrease in the size of the node, in but ii applications! And it no longer feels matted. This node has been bloated for over 20 years!!! - Melissa Medlock, Coldwater, Michigan, Us

Podiatry

DMSO tin be constructive in the handling of painful corns, calluses, ingrown toenails, bunions, hammertoes, heel spurs, and the inflammation of gouty big toes.
Varicose veins and thrombophlebitis

Topical DMSO tin whiten telangiectasias, minor dilated blood vessels near the surface of the pare. Information technology can likewise decrease the size of varicosities in the legs and the inflammation that goes with it, along with a relief of their cramping discomfort (Marvin, 1967. Blumenthal, Fuchs, 1967).

Eye bug

One drop of a 25% DMSO solution (diluted in sterile physiologic or saline solution) one time or twice per twenty-four hours is useful for eye bug, including cataracts or glaucoma.

"DMSO is amazing, I've too read various good results with using it in the eyes. Being the audacious type myself, today I diluted DMSO down to 30% and put ii drops in one of my eyes that has been having red spots effectually the iris. The crimson spots macerated drastically. The just side issue was a slight called-for sensation, similar to those drops yous become when one goes for a glaucoma test, without the side effect of dilated pupils." - DZ, The states

Headaches

DMSO is highly effective in vascular headaches and in muscular tension which so oft goes with headaches. It may exist used on hairy areas such every bit the scalp and it besides may be used near the eyes. A 90% solution is more effective (Ogden, 1967).

Mental Disorders

DMSO has been useful in the treatment of patients with the following diagnoses: (1) overexcited states (acute schizophrenic reactions, manic phase of the manic-depressive psychoses, alcoholic psychoses, symptomatic psychoses); (2) some symptoms of the chronic psychoses (autism, stereotypia, negativism, abnormal beliefs or delusional states) ; (3) severe neuroses (anxiety reactions, obsessives)( Ramírez, Luza, 1967).

McGrady called special attending to an extraordinary paper presented by Dr. Eduardo Ramirez and Dr. Segisfredo Luza of the Ayetano Heredia University in Lima, Republic of peru. Afterward extensive tests on animals and then on normal humans, Dr. Ramirez reported "injecting 50% or 80% DMSO intramuscularly into patients with acute and chronic schizophrenia" and that "of the fourteen acute cases, every single one was discharged from the hospital inside 45 days afterward the start of DMSO treatment... He said that iv of the 11 chronic cases, one of whom has been ill for fourteen years, were discharged somewhen, and the other 7 improved a great deal and were given occupational therapy... He observed rapid subtract in agitation... recession of persecution feeling, a relatively sudden trend to communicate and to stay clean.., the wane of obsessions, return to alertness, and a calmness where there had been restlessness and anxiety". (Haley, 2000)

Genitourinary disorders

DMSO has been used in the handling of a number of patients with various genitourinary disorders, including Peyronie's disease, interstitial cystitis, acute epididymitis. Some accept obtained dramatic and gratifying relief of symptoms (Persky, Steeart, 1967).

Miscellaneous

DMSO in conjunction with other treatments has shown to regress cancer in a very effective way (Ayre, 1967).

Intravenous assistants of DMSO markedly reduces pathological intestinal permeability while preserving the gut's absorption capacities (Wang et al, 1996). Considering that gut permeability ('leaky gut') has a fundamental office in chronic degenerative diseases, this is of great clinical importance.

DMSO also has excellent results in the peel of people affected with scleroderma, results which have never been observed with any other method of therapy (Scherbel et al, 1967).

Mrs. Jean Puccio of Washington, DC testified at hearings of Senator Edward Kennedy'due south sub-commission on health in 1980 on her recovery from scleroderma. Diagnosed in 1971, she was told that no medication would aid, and that she would probably soon face a wheelchair and early on expiry. By the fourth dimension she found Dr. Jacob (through word of oral fissure), she told the Senators, "I was having difficulty breathing, walking, and eating". The affliction "thickens the tissue and makes your skin and then tight you cannot move. It was difficult for me to drive, to plow the ignition in my machine or plough my body". Her dentist could not work on her for awhile because she could not open her mouth. "Now I tin open my oral cavity like anybody", she said. After her sensitized peel burned from topical application of DMSO, Dr. Jacob suggested taking it orally. "Within six months", she testified, "my condition reversed almost immediately. I can practise anything anybody else can do now" (Haley, 2000).

Hopefully, this brief overview of DMSO'due south groovy capabilities has helped to illustrate how it is indeed, the cure of our times. I'm convinced of its therapeutic power, both by my own experience and that one of scores of people, not to mention the back-upwards of published scientific literature. Its uses and applications make it a very handy chemical compound to have on your medical shelf. In pure grade, the life of DMSO is indefinite, so it may be used for years.

Troubleshooting

The garlic-similar body odor and taste in the mouth that some feel is attributable to a specific DMSO metabolite: dimethyl sulfide (DMS), a component of natural onion and garlic flavors (McKim, Strub, 2008). This tin last for i or two days and in a small number of people, peculiarly men, the odor can be very pungent. Drinking enough h2o volition aid diffuse the aroma. Other side effects - such as stomach upset, headaches, dizziness, and sedation - are very likely related to detoxification reactions prompted by the DMSO.

But purified and properly diluted DMSO should be used. When you dilute a pure DMSO solution, e'er do it in distilled water. When it is applied, the skin site also as the applying manus should be thoroughly cleaned before application. This is of utmost importance as DMSO's properties allow contaminants to be absorbed through the skin and transported into the bloodstream.

DMSO is known to be 1 of the to the lowest degree toxic substances in biology (Parcell, 2002), so any serious side furnishings should come from potential contaminants or the intake of concomintant drugs that DMSO will carry into the body. Worth repeating again, DMSO and whatsoever substance dissolved in it, will penetrate the skin, the claret-brain barrier, and other parts of the body very fast.

Remember besides that DMSO increases the furnishings of drugs similar claret thinners, steroids, heart medicines, sedatives, etc. In add-on to that, acetone or acid contagion of DMSO can atomic number 82 to serious medical consequences. Be enlightened of this trouble when buying unreliable DMSO. A pure DMSO solution will turn solid (like ice) in the refigerator inside two hours. If, when the frozen canteen is turned upside down, little rivulets of h2o menstruation through the ice, you lot probably possess the veterinary grade DMSO. This is a 90% concentration. Ten percent is distilled water (Morton, 1993).

Women are discouraged from using DMSO during pregnancy or breastfeeding, even though DMSO is used to preserve frozen human embryos. DMSO can interfere with liver part tests and give a simulated reading. That problem is easily solved by waiting a week after DMSO usage before taking the test.

Long-term use has been documented as safe. Center damage, reported in laboratory animals, has non been confirmed. Side effects such equally skin rash and itching after topical application, breaking upwardly of blood elements subsequently intravenous infusion, tin can exist avoided in large part by employing more than dilute solutions. Despite these side effects, DMSO is used equally a preservative for blood elements and stem cells (McKim, Strub, 2008).

When DMSO is diluted with water, heat is released. The bottle volition be warm to the touch. This is a temporary, harmless reaction.

Since DMSO causes dryness and scaling of the outer layer of the skin, skin diseases characterized by scaling (psoriasis) could be aggravated by the use of DMSO. But DMSO applied topically for but a few days has been useful in psoriasis. Prolonged use of DMSO for the treatment of psoriasis is not brash still, equally information technology can worsen the psoriatic condition (Engel, 1967), but DMSO taken orally is suggested.

"I'm happy to say that taking DMSO in conjunction with implementing the detoxification suggestions that were given is starting to have intendance of many of my remaining psoriasis bug. A couple areas are still being stubborn, but I've noticed a lot of full general comeback. Using DMSO topically also helped ameliorate a patch of eczema that my wife has been bothered by for quite a while." - Peter Norquest, Tucson, Arizona, United States

DMSO2, a derivative of DMSO, is ameliorate tolerated and doesn't take the odor and irritation side effects. Despite this positive aspect, it hasn't surpassed the effectiveness, fascination and popularity of DMSO. It is also known as methylsufonlmethane or MSM, an entire topic for another article past itself!

Sulfur is an element of the globe and it is essential to life, it as among the nearly prevalent elemenents in the human body. Allergic reactions to sulfur are not possible because sulfur has no protein component. When people are 'allergic to sulfur', what they really mean is that they are allergic or sensitive mainly to sure sulfur-containing drugs or proteins, virtually notably sulfa antibiotics (sulfonamides) or to sulfites (preservatives used in wines and some foods), or to foods with a loftier sulfur content (broccoli, cauliflower, garlic, onions, etc). Many individuals with allergies to sulfa drugs, sulfites, or high sulfur containing foods (like the author) do not experience problems taking DMSO, because apart from sulfur, DMSO bears no relation to these substances.

As always, proceed with circumspection, practice your homework, and consult a health care provider in instance of doubts.

References:

Ayre JE, LeGuerrier J. Some (regressive) effects of DMSO dexamethasone upon cervical cells in cervical dysplasia and carcinoma in situ. Ann N Y Acad Sci. 1967 Mar 15;141(ane):414-22.

Blumenthal LS, Fuchs Chiliad. The clinical employ of dimethyl sulfoxide on various headaches, musculoskeletal, and other general medical disorders. Ann N Y Acad Sci. 1967 Mar 15;141(ane):572-85.

Engel MF. Indications and contraindications for the use of DMSO in clinical dermatology. Ann N Y Acad Sci. 1967 Mar 15;141(1):638-45.

Goldman J. A cursory resume of clinical observations in the treatment of superficial burns, trigeminal neuralgia, acute bursitis, and acute musculo-skeletal trauma with dimethyl sulfoxide. Ann N Y Acad Sci. 1967 Mar 15;141(1):653-4.

Gordon DM. Dimethyl sulfoxide in ophthalmology, with especial reference to possible toxic effects. Ann N Y Acad Sci. 1967 Mar 15;141(1):392-401.

Haley Daniel. Politics in Healing. Potomac Valley Printing, 2000.

Jacob SW, de la Torre JC. Pharmacology of dimethyl sulfoxide in cardiac and CNS harm. Pharmacol Rep. 2009 Mar-April;61(2):225-35.

Marvin P. Interval therapy with Dimethyl Sulfoxide. Annals of the New York Academy of Sciences. Volume 141, Biological Actions of Dimethyl Sulfoxide pages 551 - 554.

McKim A.S., Strub Robert. Dimethyl Sulfoxide USP, PhEur in Approved Pharmaceutical Products and Medical Devices. Pharmaceutical Technology, May 2008.

Ogden Hard disk drive. Experiences with DMSO in treatment of headache. Ann N Y Acad Sci. 1967 Mar 15;141(1):646-8.

Parcell S. Sulfur in human nutrition and applications in medicine. Altern Med Rev. 2002 Feb;7(1):22-44.

Persky L, Steeart BH. The use of dimethyl sulfoxide in the treatment of genitourinary disorders. Ann Due north Y Acad Sci. 1967 Mar xv;141(1):551-iv.

Pezalla E. Preventing adverse drug reactions in the general population. Manag Care Interface. 2005 Oct;18(10):49-52.

Pottz GE, Rampey JH, Benjamin F.Ann- The outcome of dimethyl sulfoxide (DMSO) on antibiotic sensitivity of a grouping of medically important microorganisms: preliminary written report. Ann N Y Acad Sci. 1967 Mar 15;141(i):261-72.

Ramírez E, Luza S. Dimethyl sulfoxide in the treatment of mental patients. Ann North Y Acad Sci. 1967 Mar 15;141(i):655-67.

Sams WM Jr. The furnishings of dimethyl sulfoxide on nervus conduction. Ann N Y Acad Sci. 1967 Mar fifteen;141(1):242-7.

Sanders M. Discussion. Register of the New York Academy of Sciences. Book 141, Biological Actions of Dimethyl Sulfoxide pages 649 - 652, March 1967.

Scherbel AL, McCormack LJ, Layle JK. Further observations on the effect of dimethyl sulfoxide in patients with generalized scleroderma. (Progressive systemic sclerosis). Ann N Y Acad Sci. 1967 Mar 15;141(1):613-29.

Steinberg A. The employment of dimethyl sulfoxide as an antiinflammatory agent and steroid-transporter in diversified clinical diseases. Ann N Y Acad Sci. 1967 Mar 15;141(1):532-fifty.

Tamblyn R, Berkson Fifty, Dauphinee WD, Gayton D, Grad R, Huang A, Isaac L, McLeod P, Snell L. Unnecessary prescribing of NSAIDs and the management of NSAID-related gastropathy in medical practice. Ann Intern Med. 1997 Sep 15;127(6):429-38.

Walker Morton. DMSO Nature'due south Healer. New York: Avery, 1993.

Wang XD, Wang Q, Andersson R, Ihse I. Alterations in intestinal function in acute pancreatitis in an experimental model. Br J Surg. 1996 November;83(11):1537-43.

Well-nigh the author:
Gabriela Segura M.D. is a eye surgeon with extensive experience and interest in culling health reasearch, psychology and the homo status. She is a regular contributor to Sott.net and maintains her health website Health Matrix